Tab: Artesunate Tablets may depress bone marrow and cause reticulocytopenia.
Inj: In the mice, decreased reticulocyte and increased alkaline phosphatase in plasma.
Influence on central nervous system. In mice when give Artesunate at high dose cause decreased activity, retardation of reaction, and increase in pain threshold and caused transient lowering of body temperature.
Parenchymal damage in the mucosa of stomach and intestines.
In mice, have liver and kidney intoxication.
Damage red blood cell in bone marrow in mice.
In mice, made embryotoxicity at the mid and late stages in organogenetic period of fetal rats.